In this information and knowledge age, academies must come out from the back of the screen to the center stage of the organization. Institutional success depends on knowledge sharing (KS). Institutional success depends on knowledge sharing (KS). However, knowledge exchange within businesses would significantly impact their effectiveness as it encourages individuals to address internal issues. There have been few types of research done in the Pakistani environment to determine the impact of information technology on KS among academic professionals. Purpose–The purpose of this study is to explore the impact of information technology on knowledge sharing among faculty members of public sector higher education intuitions in Sindh province of Pakistan. Methodology: This is a quantitative study in which the authors employed a survey questionnaire to collect cross-sectional data from the faculty members of public sector higher education institutes (HEIs) of Sindh. Structural Equation Modeling (AMOS) was used to examine 335 valid questionnaires. The questions were composed of four key factors, including KS, management support, information technology infrastructure, and information technology skills as independent variables. Findings: The structural equation model (SEM) analysis shows there is a positive and significant impact of information technology infrastructure, management support, and information technology skills on knowledge sharing. Originality/value: This research’s findings offer the original contribution of information technology and knowledge sharing among faculty members of higher education institutes in developing countries.